I am currently the Medical Director of the Neonatal Intensive Care Unit (NICU) at Kentucky Children’s Hospital. As a practicing neonatologist, I commonly see the clinical course of Acute Kidney Injury (AKI) in preterm infants and believe that there are opportunities to improve care and outcomes for this vulnerable population. My research is focused on mechanisms of renal development and injury in preterm infants, as well as long-term consequences of AKI in this group. I am also interested in the role of ‘omics’ for developing precision medicine in neonatology to be applied for diagnostic purposes and monitoring disease progression and/ or response to treatment.
My goals as a physician scientist are to advance the mechanistic understanding that addresses the medical problem of preterm infant’s kidney development and injury. At present, I am studying the effect of perinatal inflammation in combination with nephrotoxic exposure during nephrogenesis in an animal model. A key aspect for my research is that it is at the interface of two disciplines: Neonatology and Nephrology. Therefore, I work in collaboration with the Division of Pediatric Nephrology at the University of Kentucky. To this end, we have developed guidelines to follow preterm infants after discharge in the NICU graduate clinic to allow early detection of chronic kidney disease (CKD) and referral to Pediatric Nephrology clinic.