May 23, 2022
This month’s article summary by Dr. Cara Slagle highlights the recent Pediatric Research publication by Dr. Matt Harer and colleagues entitled “Renal tissue oxygenation after caffeine administration in preterm neonates.” This hypothesis generating study highlights the large knowledge gaps related to neonatal AKI, renal tissue oxygenation and the need for exploration into potential solutions to mitigate AKI and its consequences. This study demonstrates caffeine administration may increase renal tissue perfusion, a known source of renal injury. It also, interestingly demonstrates variation of increase in oxygenation depending on the baseline oxygenation subgroup following caffeine administration. For more information and to read the summary, please click here.