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Project Sponsor: NIH/NIDDK
Project Title: Acute Renal Injury Sequelae in NICU Graduates (ARISING)
Neonates admitted to the neonatal intensive care unit commonly develop neonatal acute kidney injury (nAKI), which leads to death, prolonged hospitalization and perhaps chronic kidney disease (CKD). The project's central purpose is to bridge fundamental knowledge gaps in the field by determining the attributable risk of nAKI on CKD, and providing reliable and precise methods to diagnose nAKI and predict CKD early in life. At the conclusion of the study, clinicians' abilities to care for neonates and researchers' ability to conduct intervention studies designed to improve outcomes in those at risk of nAKI will be greatly enhanced.
Additional AWAKEN Support
- Cincinnati Children’s Hospital Center for Acute Care Nephrology provided funding to create and maintain the Assessment of Worldwide Acute Kidney Injury Epidemiology in Neonates (AWAKEN) study Medidata Rave electronic database.
- The Pediatric and Infant Center for Acute Nephrology (PICAN) provided support for web meetings and for the Neonatal Kidney Collaborative (NKC) steering committee annual meeting at The University of Alabama at Birmingham (UAB). PICAN is part of the Department of Pediatrics at UAB and is funded by Children’s of Alabama hospital, UAB Department of Pediatrics, UAB School of Medicine, and UAB Center for Clinical and Translational Sciences (National Institutes of Health grant UL1TR001417).
- The University of New Mexico involvement in AWAKEN was supported by the Clinical and Translational Science Center at The University of New Mexico (National Institutes of Health grant UL1TR001449) and by The University of Iowa Institute for Clinical and Translational Science (grant U54TR001356).
- The AWAKEN study investigators at the Canberra Hospital at the Australian National University Medical School were supported by the Canberra Hospital Private Practice Fund
- Investigators at University of Virginia Children’s Hospital were supported by a 100 Women Who Care Grant from the 100 Women Charitable Foundation